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INDUSTRY × Renal Insufficiency × Clear all

NCT06004661 2026-03-06

Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal Function

Phase 2 Recruiting

Renal Insufficiency

NCT04561362 2025-11-14

Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies

Phase 1/2 Active not recruiting

BreastGenitourinaryGynecologic

Urinary Bladder Neoplasms, Breast Neoplasms, Ovarian Neoplasms, Renal Insufficiency, Triple Negative Breast Neoplasms

NCT04398745 2025-05-23

DREAMM12

Phase 1 Active not recruiting

GenitourinaryPlasma cell

Kidney Failure, Chronic, Multiple Myeloma, Renal Insufficiency

NCT03098589 2025-03-30

Revlimid® Capsules Drug Use-results Surveillance (Relapsed or Refractory ATLL)

Head & NeckLymphoidOther hematologic neoplasm

Sleepiness, Arrhythmias, Cardiac, Cataract, Confusion, Coronary Artery Disease, Digestive System Diseases, Dizziness, Fatigue, Heart Failure, Hemorrhage, Hypersensitivity, Hypotension, Orthostatic, Hypothyroidism, Infections, Lymphoma, Peripheral Nervous System Diseases, Seizures, Thromboembolism, Tumor Lysis Syndrome, Neoplasms, Second Primary, Lung Diseases, Interstitial, Renal Insufficiency, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Teratogenesis

NCT02301117 2024-09-05

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment

Phase 1 Completed

Carcinoma, Renal Cell, Kidney Diseases, Kidney Neoplasms, Urologic Diseases, Renal Insufficiency

NCT03814005 2024-09-05

A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Phase 1 Completed

17 enrolled 33 charts

MyeloidOther hematologic neoplasm

Liver Diseases, Myelodysplastic Syndromes, Neoplasms, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Renal Insufficiency

NCT00113113 2024-08-02

Study of Rubitecan in Cancer Patients With Renal or Hepatic Dysfunction

Phase 1 Completed

Liver Diseases, Neoplasms, Renal Insufficiency

NCT02571036 2023-12-13

A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies

Phase 1 Completed

CNSDermatologicGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmSarcomaThoracic

Mast Cell Activation Disorders, Carcinoma, Non-Small-Cell Lung, Glioma, Leukemia, Mast-Cell, Melanoma, Neoplasms, Germ Cell and Embryonal, Penile Neoplasms, Sarcoma, Mastocytosis, Systemic, Gastrointestinal Stromal Tumors, Renal Insufficiency

NCT01575925 2022-11-04

POM Renal

Phase 1 Completed

Multiple Myeloma, Renal Insufficiency

NCT02921802 2022-06-14

A Study of Special Use Results Surveillance of Revlimid 5mg Capsules

Classical hematologyMyeloidOtherPlasma cell

Arrhythmias, Cardiac, Constipation, Diarrhea, Heart Failure, Hemorrhage, Hypersensitivity, Infections, Multiple Myeloma, Myelodysplastic Syndromes, Myocardial Infarction, Neutropenia, Peripheral Nervous System Diseases, Thrombocytopenia, Tumor Lysis Syndrome, Lung Diseases, Interstitial, Renal Insufficiency, Venous Thromboembolism, Teratogenesis

NCT02922543 2022-06-14

A Safety and Efficacy Study of Revlimid® 5 mg Capsules in Patients With Relapsed or Refractory Multiple Myeloma Who Have Received Long-term Treatment With it Under the Actual Condition of Use

Classical hematologyOtherPlasma cell

Arrhythmias, Cardiac, Constipation, Diarrhea, Heart Failure, Hemorrhage, Hypersensitivity, Infections, Multiple Myeloma, Myocardial Infarction, Neutropenia, Peripheral Nervous System Diseases, Thrombocytopenia, Tumor Lysis Syndrome, Lung Diseases, Interstitial, Renal Insufficiency, Venous Thromboembolism, Teratogenesis

NCT02045017 2021-08-27

Efficacy and Safety of Pomalidomide and Dexamethasone in RRMM Patients With Renal Insufficiency

Phase 2 Completed

Multiple Myeloma, Renal Insufficiency

NCT03172884 2021-04-28

Study of Copanlisib in Hepatic or Renal Impairment

Phase 1 Completed

30 enrolled 20 charts

Hepatic Insufficiency, Renal Insufficiency

NCT02679131 2019-11-20

To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe Renal Impairment.

Phase 1 Terminated

Other hematologic neoplasm

Recurrence, Hematologic Neoplasms, Renal Insufficiency

NCT00652626 2019-11-19

RENAL

Phase 1 Completed

31 enrolled 30 charts

LymphoidPlasma cell

Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Renal Insufficiency

NCT03097016 2018-04-26

A Study to Assess the Pharmacokinetics of CC-122 in Subjects With Mild, Moderate, and Severe Renal Impairment

Phase 1 Completed

Lymphoma, Follicular, Renal Insufficiency

NCT00483860 2017-11-13

A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal Function

Phase 1 Completed

Neoplasms, Renal Insufficiency

NCT01331941 2017-11-06

A Pharmacokinetic Study of AMG 386 in Cancer Subjects With Normal and Impaired Renal Function

Phase 1 Completed

Kidney Diseases, Renal Insufficiency

NCT00721734 2017-05-02

Study of the Safety and Pharmacokinetics of Carfilzomib in Patients With Relapsed and Refractory Multiple Myeloma and Varying Degrees of Renal Function

Phase 2 Completed

50 enrolled 33 charts

Multiple Myeloma, Renal Insufficiency, Neoplasms, Plasma Cell

NCT01853046 2017-02-20

Pharmacokinetics and Safety of Regorafenib (BAY73-4506) in Cancer Subjects With Severe Renal Impairment

Phase 1 Completed

24 enrolled 30 charts

Neoplasms, Renal Insufficiency

NCT01599013 2015-12-08

JASINT1

Phase 2 Completed

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Neoplasm Metastasis, Urogenital Neoplasms, Urologic Neoplasms, Renal Insufficiency

NCT01569815 2015-10-19

Pharmacokinetics of LCZ696 in Subjects With Mild and Moderate Renal Impairment Compared to Healthy Subjects With Normal Renal Function

Phase 1 Completed

32 enrolled 16 charts

Lymphoma, Follicular, Renal Insufficiency

NCT00418366 2015-08-19

A Study on the Effect of Kidney Disease on a Diabetes Medication (0431-008)

Phase 1 Completed

GenitourinaryLymphoid

Kidney Failure, Chronic, Lymphoma, Follicular, Renal Insufficiency

NCT02063204 2015-06-30

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Renal Impaired Subjects and Healthy Subjects

Phase 1 Completed

Renal Insufficiency

NCT01083849 2014-12-19

TOP

761 enrolled 17 charts

Hyperparathyroidism, Secondary, Neoplasm Metastasis, Renal Insufficiency, Chronic, Renal Insufficiency

NCT01504165 2014-02-04

Pharmacokinetics in Subjects With Renal Impairment

Phase 1 Completed

Lymphoma, Follicular, Renal Insufficiency

NCT00750620 2013-09-05

A Pharmacokinetic Study of YM178 in Normal Subjects and Those With Mild, Moderate, and Severe Renal Impairment

Phase 1 Completed

Lymphoma, Follicular, Renal Insufficiency

NCT01374113 2013-03-29

Safinamide Renal Impairment Trial

Phase 1 Completed

Lymphoma, Follicular, Renal Insufficiency

NCT01273597 2013-01-18

Observational Study to Evaluate the Time to Achieving the Maintenance Dose of Zemplar® (Paricalcitol Injection) in the Treatment of Patients Suffering From End-stage Renal Disease and Severe Over-reactivity of the Parathyroid Glands

60 enrolled 11 charts

Kidney Failure, Chronic, Neoplasm Metastasis, Renal Insufficiency