Clinical Trials

93 trials
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Retinoblastoma × Clear all
NCT03050268 2026-02-09

SJFAMILY

St. Jude Children's Research Hospital

Recruiting
1,500 enrolled
BreastCNSClassical hematologyDermatologicEndocrineGastrointestinalGynecologicLymphoidOther solid neoplasmSarcoma

Turcot syndrome, Juvenile polyposis syndrome, Choroid Plexus Carcinoma, GATA2 Deficiency, Basal Cell Nevus Syndrome, Colorectal Neoplasms, Hereditary Nonpolyposis, Fanconi Anemia, Hamartoma Syndrome, Multiple, von Hippel-Lindau Disease, Hodgkin Disease, Lymphoma, Non-Hodgkin, Melanoma, Neuroblastoma, Neurofibromatosis 1, Noonan Syndrome, Pancreatic Neoplasms, Paraganglioma, Peutz-Jeghers Syndrome, Pheochromocytoma, Rothmund-Thomson Syndrome, Adenomatous Polyposis Coli, Retinoblastoma, Rhabdomyosarcoma, Tuberous Sclerosis, Neurofibromatosis 2, Li-Fraumeni Syndrome, Adrenocortical Carcinoma, Multiple Endocrine Neoplasia Type 1, Multiple Endocrine Neoplasia Type 2a, Dyskeratosis Congenita, Genetic Predisposition to Disease, Anemia, Diamond-Blackfan, Carney Complex, Hereditary Breast and Ovarian Cancer Syndrome

NCT03618381 2025-11-20

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
44 enrolled
CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT04483778 2025-11-20

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
68 enrolled
CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT05687474 2025-08-12

BabyDetect

Centre Hospitalier Universitaire de Liege

Completed
6,824 enrolled
Classical hematologyEndocrineHead & NeckMyeloidOther solid neoplasm

Ataxia with vitamin E deficiency, Beta ketothiolase deficiency, Carnitine palmitoyl transferase 1A deficiency, Carnitine palmitoyl transferase 2 deficiency, dopamine beta hydroxylase deficiency, Malonic aciduria, Nephrosis, congenital, Cholestasis, progressive familial intrahepatic 1, Medium chain acyl CoA dehydrogenase deficiency, Pyridoxine-dependent epilepsy, Neonatal-onset citrullinemia type 2, Systemic carnitine deficiency, Glut1 Deficiency Syndrome, Glutaric Acidemia I, Timothy syndrome, Brown-Vialetto-Van Laere syndrome, Methylmalonic acidemia, Aromatic amino acid decarboxylase deficiency, Succinyl-CoA:3-oxoacid CoA transferase deficiency, Segawa syndrome, autosomal recessive, Neutropenia, Severe Congenital, Autosomal Recessive 3, Basal ganglia disease, biotin-responsive, Sucrase-isomaltase deficiency, congenital, Acidemia, isovaleric, 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency, HHH syndrome, Glucose-Galactose Malabsorption, Hypophosphatasia, Infantile, Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency, Carnitine-Acylcarnitine Translocase Deficiency, Hypermethioninemia, Cardiomyopathy, Familial Hypertrophic, 4, Pyridoxamine 5-Prime-Phosphate Oxidase Deficiency, Phosphoglycerate Dehydrogenase Deficiency, Trifunctional Protein Deficiency With Myopathy And Neuropathy, Acyl-CoA Dehydrogenase Family, Member 9, Deficiency of, Phosphoserine Aminotransferase Deficiency, Inflammatory Bowel Disease 25, Autosomal Recessive, 3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency, Neurodegeneration Due To Cerebral Folate Transport Deficiency, Glycogen Storage Disease XIV, Combined Pituitary Hormone Deficiency, Shwachman-Diamond Syndrome, Polymorphic Catecholaminergic Ventricular Tachycardia, Adrenal Hyperplasia, Congenital, Adrenoleukodystrophy, Anemia, Sickle Cell, Charcot-Marie-Tooth Disease, Chediak-Higashi Syndrome, Hemophilia B, Congenital Hypothyroidism, Crigler-Najjar Syndrome, Cystic Fibrosis, Cystinosis, Diabetes Mellitus, Type 2, Fanconi Syndrome, Fanconi Anemia, Fructose Intolerance, Galactosemias, Gaucher Disease, Glucosephosphate Dehydrogenase Deficiency, Glycogen Storage Disease, Glycogen Storage Disease Type II, Granulomatous Disease, Chronic, Hemophilia A, Hepatolenticular Degeneration, Homocystinuria, Hyperoxaluria, Primary, Menkes Kinky Hair Syndrome, Leukodystrophy, Metachromatic, Mucopolysaccharidosis I, Hyperlipoproteinemia Type I, Maple Syrup Urine Disease, Mucopolysaccharidosis IV, Mucopolysaccharidosis VI, Nephritis, Hereditary, Neuronal Ceroid-Lipofuscinoses, Phenylketonurias, Pseudohypoaldosteronism, Retinoblastoma, Riboflavin Deficiency, Vitamin B 12 Deficiency, Wiskott-Aldrich Syndrome, Wolman Disease, Fructose-1,6-Diphosphatase Deficiency, Severe Combined Immunodeficiency, Mucopolysaccharidosis II, Mucopolysaccharidosis VII, Stiff-Person Syndrome, alpha-Thalassemia, Diabetes Insipidus, Nephrogenic, Smith-Lemli-Opitz Syndrome, alpha 1-Antitrypsin Deficiency, Hyperglycinemia, Nonketotic, Citrullinemia, Hyperargininemia, Ornithine Carbamoyltransferase Deficiency Disease, Carbamoyl-Phosphate Synthase I Deficiency Disease, Tyrosinemias, Myasthenic Syndromes, Congenital, Biotinidase Deficiency, Holocarboxylase Synthetase Deficiency, Anemia, Diamond-Blackfan, Jervell-Lange Nielsen Syndrome, Congenital Hyperinsulinism, Andersen Syndrome, Lymphohistiocytosis, Hemophagocytic, Familial Hypophosphatemic Rickets, Aspartylglucosaminuria, Propionic Acidemia, Argininosuccinic Aciduria

NCT00445965 2024-04-04

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

Memorial Sloan Kettering Cancer Center

Phase 2 Completed
78 enrolled 11 charts
CNSDermatologicGynecologicOther solid neoplasmSarcomaThoracic

Familial ependymoma, Uveal Melanoma, Astrocytoma, Brain Neoplasms, Chondrosarcoma, Ependymoma, Glioblastoma, Glioma, Lung Neoplasms, Medulloblastoma, Melanoma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Glioma, Subependymal, Gliosarcoma, Rhabdoid Tumor, Optic Nerve Glioma, Small Cell Lung Carcinoma, Desmoplastic Small Round Cell Tumor