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Clinical Trials

11 trials
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Phase

Phase 3 6Phase 2 4Phase 1/2 1

Status

Completed 7Active not recruiting 3Recruiting 1

Sponsor Class

NIH 6OTHER 3INDUSTRY 2

Study Type

Interventional 11

Sponsor

Cancer Type

Breast 8Other solid neoplasm 1Head & Neck 1Gastrointestinal 1

Conditions

Breast Neoplasms 5Salivary Gland Neoplasms 1Malignant Solid Neoplasm 1Esophageal Neoplasms 1Carcinoma, Intraductal, Noninfiltrating 1Breast Neoplasms, Male 1Anatomic Stage I Breast Cancer AJCC v8 1Advanced Breast Carcinoma 1Adenocarcinoma Of Esophagus 1

Interventions

Cyclophosphamide 2681Cisplatin 2665Carboplatin 2462Radiotherapy 2370Paclitaxel 2264Gemcitabine 2128pembrolizumab 1993Docetaxel 1883Bevacizumab 1821Fluorouracil 1548Capecitabine 1532Oxaliplatin 1440Dexamethasone 1330Nivolumab 1300Doxorubicin 1260Rituximab 1249Magnetic Resonance Spectroscopy 1150Etoposide 1126Irinotecan 1038Leucovorin 1020Drug Therapy 999Cytarabine 964Pemetrexed 891fludarabine 889Specimen Handling 822Vincristine 793Lenalidomide 791Cetuximab 785Prednisone 785Trastuzumab 785

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements
NCT06136897 2026-03-18

Testing Trastuzumab and Pertuzumab in Patients With Higher Than Normal Copies of the HER2 Gene Found in Their Tumors (MATCH - Subprotocol J)

National Cancer Institute (NCI)

Phase 2 Active not recruiting
35 enrolled 10 charts
Other solid neoplasm

Malignant Solid Neoplasm

NCT03179904 2026-02-24

TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer

Mayo Clinic

Phase 2 Active not recruiting
17 enrolled 10 charts
Breast

Advanced Breast Carcinoma

NCT01196390 2026-02-18

Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer

National Cancer Institute (NCI)

Phase 3 Completed
203 enrolled 22 charts
Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT07407920 2026-02-12

Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
120 enrolled
Breast

Anatomic Stage I Breast Cancer AJCC v8

NCT05408845 2026-01-14

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

NRG Oncology

Phase 2 Recruiting
146 enrolled
Head & Neck

Salivary Gland Neoplasms

NCT03199885 2025-12-30

Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

National Cancer Institute (NCI)

Phase 3 Completed
190 enrolled 12 charts
Breast

Breast Neoplasms

NCT00770809 2025-08-15

Paclitaxel and Trastuzumab With or Without Lapatinib in Treating Patients With Stage II or Stage III Breast Cancer That Can Be Removed by Surgery

National Cancer Institute (NCI)

Phase 3 Completed
305 enrolled 10 charts
Breast

Breast Neoplasms, Breast Neoplasms, Male

NCT01275677 2025-07-14

Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer

National Cancer Institute (NCI)

Phase 3 Completed
3,270 enrolled 16 charts
Breast

Breast Neoplasms

NCT00769379 2025-06-12

Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy

National Cancer Institute (NCI)

Phase 3 Completed
2,014 enrolled 16 charts
Breast

Carcinoma, Intraductal, Noninfiltrating

NCT01084876 2025-02-11

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Celltrion

Phase 3 Completed
475 enrolled 25 charts
Breast

Breast Neoplasms

NCT01084863 2025-01-24

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Celltrion

Phase 1/2 Completed
143 enrolled 23 charts
Breast

Breast Neoplasms

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