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NCT03270059 2026-02-27

Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System

Phase 2 Recruiting

Brain Neoplasms, Cranial Nerve Diseases, Central Nervous System Neoplasms

NCT04369560 2025-12-17

Virtual Histology of the Bladder Wall for Bladder Cancer Staging

Phase EARLY_PHASE1 Recruiting

Urinary Bladder Neoplasms

NCT04900792 2025-12-03

XACT-Fe-GBM-01

Phase 1 Active not recruiting

Glioblastoma

NCT03347617 2025-09-09

Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With Glioblastoma

Phase 2 Terminated

52 enrolled 15 charts

Glioblastoma

NCT02070705 2025-07-31

DCE MRI in Patients With Pancreatic Cancer

Phase NA Terminated

Gastrointestinal

Pancreatic carcinoma, familial, Pancreatic Intraductal Neoplasms

NCT02631733 2025-02-10

Liposomal Irinotecan and Veliparib in Treating Patients With Solid Tumors

Phase 1 Completed

Other solid neoplasm

Malignant Solid Neoplasm

NCT01542879 2024-11-25

Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer

Phase 1/2 Recruiting

Neoplasms

NCT04682847 2024-01-31

Radiotherapy With Iron Oxide Nanoparticles (SPION) on MR-Linac for Primary & Metastatic Hepatic Cancers

Gastrointestinal

Carcinoma, Hepatocellular, Liver Cirrhosis, Liver Neoplasms

NCT01336803 2023-12-27

Osteosarcoma

Phase 2 Completed

32 enrolled 11 charts

Bone Neoplasms, Chondrosarcoma, Osteomyelitis, Osteonecrosis, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT00659126 2023-09-07

Ferumoxytol- and Gadolinium-Labeled MRI in Measuring Tumors Before or After Treatment in Patients With Primary or Metastatic Brain Tumors

Phase 2 Terminated

40 enrolled 8 charts

Brain Neoplasms

NCT03179449 2023-04-14

In Vivo Characterization of Macrophages in Pediatric Patients With Malignant Brain Tumors Using Ferumoxytol-enhanced MRI

Phase EARLY_PHASE1 Withdrawn

Childhood Brain Neoplasm

NCT03325166 2022-08-10

Pembrolizumab and Magnetic Resonance Imaging With Ferumoxytol in Treating Patients With Non-small Cell Lung Cancer and Brain Metastases

Phase 2 Terminated

2 enrolled 8 charts

Lung Carcinoma Metastatic in the Brain

NCT00978562 2022-08-03

DSC-MRI With Ferumoxytol and DCE-MRI With Gadolinium in Imaging Vascular Properties in Younger Patients With Brain Tumors

Phase EARLY_PHASE1 Completed

14 enrolled 8 charts

Childhood Brain Neoplasm

NCT00103038 2022-06-09

Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases

Phase NA Completed

155 enrolled 11 charts

Brain Neoplasms, Glioma

NCT02359097 2022-03-17

Steady State Blood Volume Maps Using Ferumoxytol Non-stoichiometric Magnetite MRI in Imaging Patients With Glioblastoma

Phase NA Completed

Glioblastoma

NCT01895829 2021-09-21

Ferumoxytol - Iron Oxide Nanoparticle Magnetic Resonance Dynamic Contrast Enhanced MRI

Phase EARLY_PHASE1 Terminated

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02857218 2021-09-16

Ferumoxytol-Enhanced MRI in Imaging Lymph Nodes in Patients With Stage IIB-IIIC Esophageal Cancer

Phase EARLY_PHASE1 Withdrawn

Gastrointestinal

Esophageal Neoplasms

NCT03280277 2021-09-10

Ferumoxytol-Enhanced MRI in Imaging Lymph Nodes in Patients With Locally Advanced Rectal Cancer

Phase EARLY_PHASE1 Terminated

Gastrointestinal

Rectal Neoplasms

NCT01663090 2020-10-19

Ferumoxytol-Enhanced MRI in Adult/Pedi Sarcomas

Phase NA Withdrawn

Sarcoma

NCT01815333 2020-10-19

Clinical and Technical Feasibility of a Ultrasuperparamagnetic Nanoparticle Iron Oxide (USPIO)-Enhanced Magnetic Resonance Lymph Node Imaging

Phase NA Completed

10 enrolled 5 charts

Cancer of Lymph Node

NCT01770353 2019-11-27

MM-398 (Nanoliposomal Irinotecan, Nal-IRI) to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment

Phase 1 Completed

45 enrolled 33 charts

BreastGastrointestinalGynecologicHead & Neck

Head and Neck Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT02141490 2019-09-06

Study of Ferumoxytol Enhanced MRI for Detecting Lymph Node Metastases in Prostate, Bladder, and Kidney Cancers

Phase 2 Completed

43 enrolled 12 charts

Urinary Bladder Neoplasms, Kidney Neoplasms, Prostatic Neoplasms

NCT02253602 2019-01-16

IMPROVE

Phase NA Completed

Gastrointestinal

Esophageal Neoplasms

NCT01296139 2018-07-05

Ferumoxytol Enhanced MRI for the Detection of Lymph Node Involvement in Prostate Cancer

Phase 1 Completed

Prostatic Neoplasms

NCT02466828 2018-04-18

qBOLD MRI of Glioblastoma Multiforme for Assessment of Tumor Hypoxia.

Phase EARLY_PHASE1 Completed

Hypoxia, Glioblastoma

NCT02452216 2017-08-31

Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS

Phase EARLY_PHASE1 Completed

Ischemic Stroke, Hemorrhagic Stroke, Brain Injuries, Brain Neoplasms, Central Nervous System Infections, Neurodegenerative Diseases, Central Nervous System Vascular Malformations

NCT00660543 2017-05-16

MRI Study With Ferumoxytol in Assessing Early Response in Patients With Glioblastoma Multiforme Receiving Temozolomide and Radiation Therapy

Phase NA Completed

14 enrolled 6 charts

Adult Brain Glioblastoma

NCT01983371 2016-05-20

Diagnostic Accuracy of Ferumoxytol-Enhanced MRI for Detecting Lymph Node Metastases in Colorectal Cancer

Phase NA Withdrawn

Gastrointestinal

Colorectal Neoplasms

NCT02689401 2016-05-13

MRI Iron Oxide Imaging for Lymph Node Staging in Esophageal Cancer

Phase 1 Withdrawn

Gastrointestinal

Esophageal Neoplasms