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Clinical Trials

27 trials
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Phase

Phase 2 15Phase 3 5Phase 1 3Phase NA 2Phase 4 2

Status

Completed 19Terminated 3Recruiting 3Unknown 1Active not recruiting 1

Sponsor Class

INDUSTRY 14OTHER 12OTHER_GOV 1

Study Type

Interventional 27

Sponsor

Cancer Type

Dermatologic 14Head & Neck 3Lymphoid 2Gastrointestinal 2Breast 2Thoracic 1Gynecologic 1

Conditions

Keratosis, Actinic 11Head and Neck Neoplasms 3Condylomata Acuminata 3Mycosis Fungoides 2Lymphoma, T-Cell, Cutaneous 2Exanthema 2Colorectal Neoplasms 2Breast Neoplasms 2Wounds and Injuries 1Warts 1Virus Diseases 1Usual Type Vulval Intraepithelial Neoplasia (uVIN) 1Squamous Intraepithelial Lesions 1Skin Neoplasms 1Sexually Transmitted Diseases 1Radiodermatitis 1Parapsoriasis 1Papillomavirus Infections 1Neoplasms 1Keratosis, Seborrheic 1Hypogonadism 1Hemangioma, Cavernous 1Hemangioma 1Fatigue 1Eunuchism 1Dermatitis, Contact 1Carcinoma, Squamous Cell 1Carcinoma, Non-Small-Cell Lung 1Cancer Pain 1Breast Carcinoma In Situ 1

Interventions

Cyclophosphamide 2681Cisplatin 2665Carboplatin 2462Radiotherapy 2370Paclitaxel 2264Gemcitabine 2128pembrolizumab 1993Docetaxel 1883Bevacizumab 1821Fluorouracil 1548Capecitabine 1532Oxaliplatin 1440Dexamethasone 1330Nivolumab 1300Doxorubicin 1260Rituximab 1249Magnetic Resonance Spectroscopy 1150Etoposide 1126Irinotecan 1038Leucovorin 1020Drug Therapy 999Cytarabine 964Pemetrexed 891fludarabine 889Specimen Handling 822Vincristine 793Lenalidomide 791Cetuximab 785Prednisone 785Trastuzumab 785

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements
NCT04570956 2026-01-23

Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk

Mayo Clinic

Phase 2 Terminated
65 enrolled
Breast

Breast Carcinoma In Situ, Breast Neoplasms

NCT04173247 2025-03-17

Study of KeraStat Cream for Radiation Dermatitis During Head and Neck Radiotherapy

Wake Forest University Health Sciences

Phase NA Completed
28 enrolled 12 charts
Head & Neck

Head and Neck Neoplasms, Radiodermatitis

NCT04301765 2025-03-11

TEMEC

Seattle Institute for Biomedical and Clinical Research

Phase 2 Recruiting
230 enrolled

Eunuchism, Fatigue, Hypogonadism, Neoplasms

NCT05387525 2025-02-11

AKtive

Almirall, S.A.

Phase 4 Active not recruiting
447 enrolled
Dermatologic

Keratosis, Actinic

NCT06745999 2024-12-24

Cryotherapy in Combination with Red Light PDT for Actinic Keratosis of Full Face

Psoriasis Treatment Center of Central New Jersey

Phase 4 Recruiting
40 enrolled
Dermatologic

Keratosis, Actinic

NCT06577311 2024-08-29

Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)

The Center for Clinical and Cosmetic Research

Phase 2 Recruiting
20 enrolled
DermatologicGynecologic

Squamous Intraepithelial Lesions, Carcinoma, Squamous Cell, Skin Neoplasms

NCT05800834 2023-09-28

MorphineGEL

Instituto Nacional de Cancer, Brazil

Phase 2 Unknown
106 enrolled
BreastHead & Neck

Cancer Pain, Breast Neoplasms, Head and Neck Neoplasms, Wounds and Injuries

NCT02462187 2023-04-06

Topical NVN1000 for the Treatment of External Genital and Perianal Warts

Novan, Inc.

Phase 2 Completed
108 enrolled 19 charts

Condylomata Acuminata

NCT01874860 2022-12-01

Skin Rash Study Before Chemotherapy in Colorectal & Head and Neck Cancer Patients

University of Louisville

Phase 2 Completed
24 enrolled
GastrointestinalHead & Neck

Head and Neck Neoplasms, Colorectal Neoplasms

NCT03380026 2021-11-24

MIDAS

Rochester Skin Lymphoma Medical Group, PLLC

Phase 2 Completed
28 enrolled 8 charts
DermatologicLymphoid

Dermatitis, Contact, Mycosis Fungoides, Lymphoma, T-Cell, Cutaneous

NCT03826550 2019-02-01

Therapeutic Equivalence of Diclofenac Sodium Gel 3% vs Solaraze ® in the Treatment of Actinic Keratosis

Encube Ethicals Pvt. Ltd.

Phase 3 Completed
655 enrolled
Dermatologic

Keratosis, Actinic

NCT02724254 2018-07-20

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Twice Daily Topical Applications of AP611074 5% Gel for up to 16 Weeks in Condyloma Patients

Vaxart

Phase 2 Completed
218 enrolled

Condylomata Acuminata, Sexually Transmitted Diseases, Virus Diseases, Papillomavirus Infections

NCT03508856 2018-04-26

Clinical and Histologic Evaluation of Picato 0.15% Gel in the Cosmetic Improvement of Photoaged Skin

Skin Laser & Surgery Specialists

Phase NA Completed
23 enrolled
Dermatologic

Keratosis, Actinic

NCT02596074 2017-08-03

Pharmacodynamics, Safety/Tolerability and Efficacy of Topical Omiganan in Patients With uVIN

Maruho Co., Ltd.

Phase 2 Completed
12 enrolled

Usual Type Vulval Intraepithelial Neoplasia (uVIN)

NCT02748902 2017-07-17

Exploratory Study of Efficacy and Safety of Ingenol Mebutate 0.05% Gel for Common Warts on the Hands.

TCR Medical Corporation

Phase 1 Completed
16 enrolled

Warts

NCT02849262 2017-03-31

Pharmacodynamics, Safety and Efficacy of Topical Omiganan in Patients With External Genital Warts

Maruho Co., Ltd.

Phase 2 Completed
24 enrolled

Condylomata Acuminata

NCT02145884 2017-02-13

Topical Timolol Gel for the Treatment of Infantile Hemangiomas

Rady Children's Hospital, San Diego

Phase 2 Completed
26 enrolled

Hemangioma, Hemangioma, Cavernous

NCT01931150 2017-01-13

Study of Prophylactic Topical Dapsone 5% Gel Versus Moisturizer for Cetuximab-induced Papulopustular (Acneiform) Rash in Patients With mCRC or HNSCC Without Previous or Concurrent RT

Memorial Sloan Kettering Cancer Center

Phase 3 Completed
11 enrolled 7 charts
Gastrointestinal

Exanthema, Colorectal Neoplasms

NCT00850681 2015-09-09

A Study to Evaluate the Photoallergic Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers

Peplin

Phase 1 Completed
50 enrolled
Dermatologic

Keratosis, Actinic

NCT00850811 2015-09-09

A Study to Evaluate the Photoirritation Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers

Peplin

Phase 1 Completed
30 enrolled
Dermatologic

Keratosis, Actinic

NCT00742391 2015-03-06

A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations

Peplin

Phase 3 Completed
255 enrolled 9 charts
Dermatologic

Keratosis, Actinic

NCT00852137 2015-03-06

A Study to Evaluate the Pharmacokinetics of PEP005 (Ingenol Mebutate) Gel, 0.05%, When Applied in a Maximal Use Setting to the Dorsal Aspect of the Forearm in Patients With Actinic Keratosis

Peplin

Phase 2 Completed
16 enrolled 9 charts
Dermatologic

Keratosis, Actinic

NCT00915551 2015-03-06

A Multi-Center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp)

Peplin

Phase 3 Completed
278 enrolled 9 charts
Dermatologic

Keratosis, Actinic

NCT00942604 2015-03-06

A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations

Peplin

Phase 3 Completed
203 enrolled 8 charts
Dermatologic

Keratosis, Actinic

NCT00322296 2013-04-16

Phase II Trial to Evaluate the Efficacy of Topical Bexarotene Gel in Patients With Parapsoriasis

Fox Chase Cancer Center

Phase 2 Terminated
8 enrolled
DermatologicLymphoid

Mycosis Fungoides, Parapsoriasis, Lymphoma, T-Cell, Cutaneous

NCT00343187 2011-05-30

A Phase II Study of ACZONE™ (Dapsone) Gel, 5% As a Treatment For Tarceva® (Erlotinib)Related Rash

Allergan

Phase 2 Terminated
2 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Exanthema

NCT01214564 2011-01-25

Study to Evaluate the Safety and Efficacy of PEP005(Ingenol Mebutate) Gel, 0.05%, in Patients With Seborrhoeic Keratosis

Peplin

Phase 2 Completed
24 enrolled
Dermatologic

Keratosis, Seborrheic, Keratosis, Actinic

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