Announcements Trials
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Clinical Trials

8 trials
RecentStart dateEnrollment
HLX07 × Clear all

Phase

Phase 2 4Phase 1 2Phase 2/3 1Phase 1/2 1

Status

Unknown 4Not yet recruiting 3Completed 1

Sponsor Class

INDUSTRY 8

Study Type

Interventional 8

Sponsor

Cancer Type

Thoracic 2Gastrointestinal 2Tumor-Agnostic 1Other solid neoplasm 1Head & Neck 1

Conditions

Stomach Neoplasms 1Squamous NSCLC 1Squamous Cell Carcinoma of Head and Neck 1Solid Tumor 1Small Cell Lung Carcinoma 1Neoplasm Metastasis 1Colonic Neoplasms 1CRC 1

Interventions

Cyclophosphamide 2681Cisplatin 2665Carboplatin 2462Radiotherapy 2370Paclitaxel 2264Gemcitabine 2128pembrolizumab 1993Docetaxel 1883Bevacizumab 1821Fluorouracil 1548Capecitabine 1532Oxaliplatin 1440Dexamethasone 1330Nivolumab 1300Doxorubicin 1260Rituximab 1249Magnetic Resonance Spectroscopy 1150Etoposide 1126Irinotecan 1038Leucovorin 1020Drug Therapy 999Cytarabine 964Pemetrexed 891fludarabine 889Specimen Handling 822Vincristine 793Lenalidomide 791Cetuximab 785Prednisone 785Trastuzumab 785

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements
NCT07358585 2026-01-22

A Phase Ib/II Study to Evaluate HLX43 Combined With HLX07 or Serplulimab in Patients With Advanced or Metastatic Colorectal Cancer

Shanghai Henlius Biotech

Phase 1/2 Not yet recruiting
126 enrolled
Gastrointestinal

Colonic Neoplasms

NCT07318883 2026-01-06

A Phase II/III Clinical Study to Evaluate HLX07 in Combination With Serplulimab and Chemotherapy Versus Placebo in Combination With Serplulimab or Pembrolizumab and Chemotherapy as First-Line Treatment in Advanced Squamous Non-Small Cell Lung Cancer

Shanghai Henlius Biotech

Phase 2/3 Not yet recruiting
720 enrolled
Thoracic

Squamous NSCLC

NCT04297995 2023-08-08

Evaluate the Efficacy and Safety of HLX10 in Combination With HLX07 in Patients With Advanced Head and Neck Tumors

Shanghai Henlius Biotech

Phase 2 Unknown
131 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT05360368 2022-05-05

HLX07(Anti-EGFR mAb) in Patients With Advanced or Metastatic Solid Tumors

Shanghai Henlius Biotech

Phase 1 Unknown
24 enrolled
Other solid neoplasm

Solid Tumor

NCT05354700 2022-05-04

A Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy in Patients With Extensive Small Cell Lung Cancer

Shanghai Henlius Biotech

Phase 2 Unknown
20 enrolled
Thoracic

Small Cell Lung Carcinoma

NCT05239650 2022-05-03

Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07+HLX10 +mFOLFOX6 or HLX07 Monotherapy in Patients With mCRC

Shanghai Henlius Biotech

Phase 2 Not yet recruiting
50 enrolled

CRC

NCT05246982 2022-05-02

HLX07+HLX10+Chemotherapy or HLX07 Monotherapy in Patients With Advanced Metastatic Gastric Cancer

Shanghai Henlius Biotech

Phase 2 Unknown
40 enrolled
Gastrointestinal

Stomach Neoplasms

NCT02648490 2019-07-30

An Open-label, Phase 1 Study to Determine the Maximum Tolerated Dose of HLX07,in Patients With Advanced Solid Cancers

Henlix, Inc

Phase 1 Completed
19 enrolled
Tumor-Agnostic

Neoplasm Metastasis

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