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Clinical Trials

6 trials
RecentStart dateEnrollment
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Phase

Phase 2 3Phase 1 3

Status

Completed 3Withdrawn 1Terminated 1Active not recruiting 1

Sponsor Class

OTHER 4INDUSTRY 2

Study Type

Interventional 6

Sponsor

Cancer Type

Head & Neck 4Thoracic 1Gynecologic 1Genitourinary 1Gastrointestinal 1

Conditions

Squamous Cell Carcinoma of Head and Neck 4Head and Neck Neoplasms 2Uterine Cervical Dysplasia 1Recurrence 1Neoplasms 1Neoplasm Metastasis 1Mouth Neoplasms 1Carcinoma, Transitional Cell 1Carcinoma, Squamous Cell 1Carcinoma, Renal Cell 1Carcinoma, Non-Small-Cell Lung 1Carcinoma, Hepatocellular 1

Interventions

Cyclophosphamide 2848Cisplatin 2837Carboplatin 2635Radiotherapy 2522Paclitaxel 2424Gemcitabine 2263pembrolizumab 2099Docetaxel 1978Bevacizumab 1966Fluorouracil 1660Capecitabine 1640Oxaliplatin 1551Dexamethasone 1417Nivolumab 1394Doxorubicin 1349Rituximab 1338Magnetic Resonance Spectroscopy 1229Etoposide 1198Irinotecan 1122Leucovorin 1096Drug Therapy 1062Cytarabine 1010Pemetrexed 944fludarabine 933Specimen Handling 875Vincristine 857Prednisone 851Lenalidomide 838Trastuzumab 837Cetuximab 831

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements
NCT03655002 2025-06-17

IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer

City of Hope Medical Center

Phase 1 Active not recruiting
8 enrolled
Gastrointestinal

Carcinoma, Hepatocellular

NCT03267680 2025-04-13

IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3

University of Southern California

Phase 2 Terminated
10 enrolled 19 charts
Gynecologic

Uterine Cervical Dysplasia

NCT02609386 2024-01-30

INSPIRE

Brooklyn ImmunoTherapeutics, LLC

Phase 2 Completed
105 enrolled 17 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms

NCT03758781 2023-04-14

IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Completed
12 enrolled
GenitourinaryHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Neoplasm Metastasis, Recurrence

NCT00210470 2020-12-11

A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer

Brooklyn ImmunoTherapeutics, LLC

Phase 2 Completed
27 enrolled 16 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Mouth Neoplasms

NCT03575234 2019-08-28

Nivolumab & IRX-2 With Surgery for Resectable Stage III-IVA Oral Cavity Cancer or HPV-Positive Oropharyngeal Cancer

Emory University

Phase 1 Withdrawn
Head & Neck

Squamous Cell Carcinoma of Head and Neck

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