Clinical Trials

Lymphoma

NCT01746173 2023-01-30

CHOEP + High Dose Therapy + Auto SCT for T-Cell Lymphoma

Phase 2 Terminated

5 enrolled 7 charts

Lymphoma, T-Cell

NCT04552743 2022-09-10

MGTA-145 + Plerixafor in the Mobilization of Hematopoietic Stem Cells for Autologous Transplantation in Multiple Myeloma

25 enrolled 14 charts

Multiple Myeloma

NCT02703779 2021-06-18

Exploratory Trial to Estimate Proportion of Patients With Tumor Cell Contaminated Leukapheresis Products With and Without Bortezomib With In-vivo Purging - Multiple Myeloma (MM)

101 enrolled 11 charts

Multiple Myeloma

NCT01753453 2021-02-23

An Exploratory Safety Study to Investigate the Extent of Tumor Cell Mobilization (TCM) After Use of G-CSF Alone or G-CSF Plus Plerixafor in Multiple Myeloma (MM) Patients Who May be Poor Mobilizers of Stem Cells

23 enrolled

Multiple Myeloma

NCT00822770 2020-10-14

Plerixafor and Granulocyte Colony-stimulating Factor (G-CSF) With Busulfan, Fludarabine and Thymoglobulin

MyeloidOther hematologic neoplasm

47 enrolled 8 charts

Graft vs Host Disease, Leukemia, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute

NCT04058145 2020-09-07

AMD3100 Plus Pembrolizumab in Immune Checkpoint Blockade Refractory Head and Neck Squamous Cell Carcinoma

Phase 2 Withdrawn

Head & Neck

Head and Neck Neoplasms

NCT03506802 2020-07-24

NYSCT MM

Phase 1 Withdrawn

LymphoidOther hematologic neoplasm

Multiple Myeloma

NCT03277209 2020-03-02

To Assess the Safety of Continuous IV Administration of Plerixafor and Assess Impact on the Immune Microenvironment in Patients With Pancreatic, Ovarian and Colorectal Adenocarcinomas

Phase 1 Terminated

2 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT02605460 2020-01-14

Chemo Sensitization Before Hematopoietic Stem Cell Transplantation in Patients With Acute Leukemia in Complete Remission

Phase 2 Unknown

20 enrolled

Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01146834 2019-12-27

Trial of Three Stem Cell Mobilization Regimens for Multiple Myeloma

Phase 3 Completed

47 enrolled 12 charts

Multiple Myeloma

NCT02682953 2019-12-11

Hyperbaric Oxygen Therapy for Hematopoietic Progenitor Cell Collection in Poor Mobilizers

Phase 2 Withdrawn

Lymphoma, Multiple Myeloma

NCT01160354 2019-08-28

Plerixafor and Clofarabine in Frontline Treatment of Elderly Patients With Acute Myelogenous Leukemia (AML)

Phase 1/2 Terminated

22 enrolled 9 charts

Leukemia, Leukemia, Myeloid, Acute

NCT02179970 2019-07-23

CAM-PLEX

GastrointestinalGynecologic

26 enrolled

Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT01408043 2019-06-14

Etoposide, Filgrastim, and Plerixafor in Improving Stem Cell Mobilization in Treating Patients With Non-Hodgkin Lymphoma

Phase NA Terminated

25 enrolled 15 charts

DermatologicLymphoidOther hematologic neoplasm

Burkitt Lymphoma, Immunoblastic Lymphadenopathy, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell

NCT02343666 2018-11-20

HIV-Resistant Gene Modified Stem Cells and Chemotherapy in Treating Patients With Lymphoma With HIV Infection

Phase 1 Withdrawn

Hodgkin Disease, Lymphoma, Non-Hodgkin

NCT01977677 2018-10-23

Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma

30 enrolled 11 charts

CNSSarcoma

Glioblastoma, Glioma, Medulloblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT01319864 2018-09-07

POETIC Plerixafor as a Chemosensitizing Agent for Relapsed Acute Leukemia and MDS in Pediatric Patients

20 enrolled

Leukemia, Recurrence, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute

NCT01547806 2018-03-07

Collection of Transplant Stem Cells for Plasma Cell Myeloma

49 enrolled 17 charts

Multiple Myeloma

NCT01373229 2018-02-05

Lenalidomide + Plerixafor in Previously Treated Chronic Lymphocytic Leukemia (CLL)

LymphoidOther hematologic neoplasm

21 enrolled 10 charts

Leukemia, Lymphocytic, Chronic, B-Cell

NCT01097057 2018-01-23

Rituximab, Combination Chemotherapy, Filgrastim (G-CSF), and Plerixafor in Treating Patients With Non-Hodgkin Lymphoma Undergoing Mobilization of Autologous Peripheral Blood Stem Cells

20 enrolled 9 charts

Lymphoma, Non-Hodgkin

NCT01339039 2017-11-17

Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Glioma

Phase 1 Terminated

26 enrolled

CNS

Astrocytoma, Oligodendroglioma

NCT03244930 2017-08-10

Low Dose Plerixafor Plus G-CSF in Mobilizing Stem Cells for Autologous Peripheral Blood Transplantation

Phase 2 Unknown

20 enrolled

Hodgkin Disease, Lymphoma, Non-Hodgkin, Neoplasms, Plasma Cell

NCT01403896 2017-08-02

Healthy Donor Study II - Comparing Plerixafor With G-CSF and Plerixafor

10 enrolled

Lymphoma

NCT01339572 2017-08-01

Clinical And Economic Impact Of Upfront Plerixafor In Autologous Transplantation

72 enrolled

Lymphoma, Non-Hodgkin, Multiple Myeloma

NCT02098109 2017-07-18

Non-inferiority Study of XM02 Filgrastim (Granix) and Filgrastim (Neupogen) in Combination With Plerixafor for Autologous Stem Cell Mobilization in Patients With Multiple Myeloma or Non-Hodgkin Lymphoma

100 enrolled 18 charts

DermatologicLymphoidMyeloidOther hematologic neoplasmPlasma cell

Lymphoma, Non-Hodgkin, Multiple Myeloma

NCT01076270 2017-06-28

Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Phase NA Terminated

1 enrolled 7 charts

Congenital Abnormalities, Blast Crisis, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Mycosis Fungoides, Myeloproliferative Disorders, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

NCT00241358 2017-06-06

Study Evaluating AMD3100 for Transplantation of Sibling Donor Stem Cells in Patients With Hematological Malignancies

LymphoidMyeloidOther hematologic neoplasmPlasma cell

92 enrolled 13 charts

Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01158118 2017-06-05

Plerixafor and Sargramostim (GM-CSF) for Mobilization of Allogeneic Sibling Donors

LymphoidMyeloidOther hematologic neoplasmPlasma cell

48 enrolled 17 charts

Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01288573 2017-05-16

A Combined Study in Pediatric Cancer Patients for Dose Ranging and Efficacy/Safety of Plerixafor Plus Standard Regimens for Mobilization Versus Standard Regimens Alone

LymphoidOther hematologic neoplasmPlasma cell

46 enrolled

CNS

Brain Neoplasms, Neuroblastoma

NCT01610999 2017-05-09

Pilot Study of Lymphoid Tumor Microenvironmental Dysruption Prior to Autologous Stem Cell Transplantation

Phase 1 Terminated

7 enrolled

Lymphoma, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell

NCT02200380 2017-04-07

A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant Pairs

Phase 2 Terminated

36 enrolled

LymphoidMyeloidOther hematologic neoplasm

Hodgkin Disease, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00906945 2017-04-04

Chemosensitization With Plerixafor Plus G-CSF in Acute Myeloid Leukemia

39 enrolled 19 charts

Leukemia, Myeloid, Acute

NCT00943943 2017-03-29

Granulocyte-colony Stimulating Factor (G-CSF) and Plerixafor Plus Sorafenib for Acute Myelogenous Leukemia (AML) With FLT3 Mutations

33 enrolled

Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute

NCT00733824 2017-03-09

Intravenous AMD3100 for Collection of Autologous Peripheral Blood Stem Cells in Patients With Lymphoma

61 enrolled 11 charts