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NCT03878849 2025-08-28Investigation of the Anti-tumor Effect of 2X-121 in Patients With Recurrent, Advanced Ovarian CancerAllarity TherapeuticsPhase 2 Recruiting40 enrolled
NCT03562832 2025-01-23Investigation of Anti-tumour Effect and Tolerability of the PARP Inhibitor 2X-121 in Patients With Metastatic Breast Cancer Selected by the 2X-121 DRPAllarity TherapeuticsPhase 2 Completed20 enrolled
NCT01618136 2023-06-18An Open-Label, Multicenter, Phase 1/2 Study of Poly(ADP-Ribose) Polymerase (PARP) Inhibitor E7449 as Single Agent in Subjects With Advanced Solid Tumors or With B-cell Malignancies and in Combination With Temozolomide (TMZ) or With Carboplatin and Paclitaxel in Subjects With Advanced Solid TumorsEisai Inc.Phase 1/2 Completed41 enrolled
NCT02396433 2015-08-25Combination of Carboplatin, Eribulin Mesylate, and E7449 in BRCA-Related CancersThe University of Texas Health Science Center at San AntonioPhase 1/2 Withdrawn